About E2BIO

Main field of study

Conducting pharmacotoxicity research on new drugs, cosmetics, and health functional foods

A Study on the Alternative Method of Animal Experiment, Skin Toxicity/Pharmacopoeia, and Circulatory Toxicity

Thesis and Patents

16-Kauren-2-beta-18,19-triol inhibits melanosome transport in melanocytes by down-regulation of melanophilin expression

Antithrombotic effect of SP-8008, a benzoic acid derivative, through the selective inhibition of shear stress-induced platelet aggregation

Ccrn4l as a pre-dose marker for prediction of cisplatin-induced hepatotoxicity susceptibility

Marine natural products with monoamine oxidase (MAO) inhibitory activity

Me-too validation study for in vitro skin irritation test with a reconstructed human epidermis model, KeraSkin™ for OECD test guideline 439

Arsenic May Act as a Pro-Metastatic Carcinogen Through Promoting Tumor Cell-Induced Platelet Aggregation

Main field of study

Research on the discovery of new natural substances and the development of cosmetics materials for the treatment of diseases

Finding new antibiotics to treat antibiotic-resistant bacteria, tuberculosis bacteria/pathogenic bacteria infection

A Study on the discovery of cancer prevention effective substances from natural materials and the mechanism of action

Natural substances for treatment of central nervous system(CNS) disorders

Analysis of the components and structures of natural substances of various efficacy for the development of cosmetics materials

Thesis and Patents

Mar. Drugs, 2017, 15, 138, Anti-Pigmentary Effect of (-)-4-Hydroxysattabacin from the Marine-Derived Bacterium Bacillus sp.

Org. Lett., 2016, 9, 2256, Ansalactams B–D Illustrate Further Biosynthetic Plasticity within the Ansamycin Pathway

J. Nat Prod., 2015, 78, 368, Monanchosterols A and B, Bioactive Bicyclo[4.3.1]steroids from a Korean Sponge Monanchora sp.

Within the last 5 years, 30 papers on the structure and efficacy of natural substances have been kept (including co-authors)

Composition containing 4-hydroxysattabacin (patent registration, KR101704922B1- SK Bioland technology transfer)

Prevention, improvement or treatment and prevention of pigmentation containing acremondin E (patent registration - EIR technology transfer)

E2BIO Co., Ltd. which has been certified as one of the few research institutes in Korea, aims to replace cosmetics with high side effects due to existing chemical ingredients by developing high-function, low-side effect natural material whitening functional cosmetics through affiliated research centers. In addition, a research team consisting of Professor Lim Kyoung-min of Ewha Womans University, Professor Nam Sang-jip, and Kwon Young-il, the Research Director, participates as a technical advisor in the development of cosmetics, and holds patented technology for natural substances derived from marine sediment.

BUSINESS

Secured key talents for research and development

Possession of patent technology for natural substances

Ewha Womans University's recognized research institute

Anthranilic acid, a newly discovered raw material by E2BIO, is excellent in inhibiting meanin production and in hibiting tyrosinase expression, thus preventing and improving skin whitening or pigmentation, and can be used for treatment.

3 times whitening effect

37% inhibitory activity at 25ppm and 45% inhibitory activity at 10ppm were confirmed, demonstrating three times better inhibitory effect that arbutin, a chemical raw material.

What is anthranilic acid?

Anthranilic acid is a new raw material for natural materials derived from marine sediment soil newly discovered by E2BIO, and is a natural whitening functional ingredient extracted with only E2BIO's patented technology.

E2BIO's VISION

E2BIO's vision is to be recognized by people who have been tamed at the standards and eye level of imported cosmetics.